arrow-downarrow-rightarrow-upback-arrowchecklistcloseAsset 5cpd-clockcpd-competenciescpd-cv-buildcpd-keyAsset 3cpd-other-pointscpd-previous-skillscpd-question-markreject2cpd-skillscpd-step-completecpd-submitcpd-updated-skillsddpm-closeddpm-starenvelopefacebookfilesglobegraphlinkedinmembermenunode-triangle-borderlessnode-trianglepluspm-clinicalpm-cmcpm-collapsepm-deliverypm-downloadpm-expandpm-global-accesspm-infopm-partnerspm-regulatorypm-researchpm-strategyrounded-arrow-rightArtboard 1speech-bubblesstarstar2triangletwitteryoutube
We use cookies to track visits to our website, and we don't store any of your personal details. Find out more
The Global Health Network The Global Health Network WHO Collaborating Centre
www.tghn.org

Not a member?

Find out what The Global Health Network can do for you. Register now.

More
Less

Member Sites A network of members around the world. Join now.

  • 1000 Challenge
  • ODIN Wastewater Surveillance Project
  • CEPI Technical Resources
  • UK Overseas Territories Public Health Network
  • MIRNA
  • Global Malaria Research
  • Global Snakebite Research
  • Global Outbreaks Research
  • Vivli Knowledge Hub
  • Sub-Saharan Congenital Anomalies Network
  • Global Health Data Science
  • Africa CDC
  • AI for Global Health Research
  • MRC Clinical Trials Unit at UCL
  • ARCH
  • IHR-SP
  • Virtual Biorepository
  • CONNECT
  • Rapid Support Team
  • The Global Health Network Africa
  • The Global Health Network Asia
  • The Global Health Network LAC
  • The Global Health Network MENA
  • Global Health Bioethics
  • Global Pandemic Planning
  • ACROSS
  • EPIDEMIC ETHICS
  • Global Vector Hub
  • PANDORA
  • Global Health Economics
  • LactaHub – Breastfeeding Knowledge
  • Global Birth Defects
  • Fiocruz
  • Antimicrobial Resistance (AMR)
  • Human Infection Studies
  • EDCTP Knowledge Hub
  • PediCAP
  • CHAIN Network
  • ALERRT
  • Brain Infections Global
  • Research Capacity Network
  • Global Research Nurses
  • mesh
  • ZIKAlliance
  • ZikaPLAN
  • TDR Knowledge Hub
  • Global Health Coordinators
  • Global Health Laboratories
  • Global Health Methodology Research
  • Global Health Social Science
  • Global Health Trials
  • Zika Infection
  • Mother Child Health
  • Global Musculoskeletal
  • Global Pharmacovigilance
  • Global Pregnancy CoLab
  • INTERGROWTH-21ˢᵗ
  • ISARIC
  • WEPHREN
  • East African Consortium for Clinical Research
  • WANETAM
  • CANTAM
  • TESA
  • GBS
  • Women in Global Health Research
  • HeLTI
  • Global Health Research Management
  • Coronavirus

Research Tools Resources designed to help you.

  • Site Finder
  • Process Map
  • Global Health Training Centre
  • Resources Gateway
  • Global Health Research Process Map
East African Consortium for Clinical Research
  • Home
    • About
    • Secretariat
    • Partners
    • EACCR 1
    • EACCR2
    • Network of networks
    • Contact Us
    • Symposium
    • Translate Site
  • Work Packages
  • Get Involved
  • Events & Workshops
  • Toolkits
  • Training
  • Resources
    • Ebola
  • Your Career
  • News
  • Other Networks
EACCR Banner. - TGHN

EACCR2

EACCR Banner. TGHN
  • About
  • Secretariat
  • Partners
  • EACCR 1
  • EACCR2
  • Network of networks
  • Contact Us
  • Symposium
  • Translate Site

EACCR2

About EACCR2-RMS

In January 2010, the European and Developing Countries Clinical Trials Partnership (EDCTP) funded the East African Consortium for Clinical Research (EACCR) to initiate a Reciprocal Monitoring Scheme (RMS) in Eastern Africa. This is an innovative practical and affordable scheme for strategic quality management of health research in Africa. The scheme provides mentorship for monitoring the quality and ethics of health research.

WHY RMS

  • The scheme provides pragmatic ways of ensuring that trials are conducted in accordance with protocols and established standard operating procedures (SOPs); produced reliable data and accurate results; complied with relevant regulations and safeguarded the rights, safety and wellbeing of participants.
  • It is an accessible regional pool of trained and experienced health professionals who monitor trials using standardized tools in mutual cross-site visits for strategic quality management and exchange of best practices as a planned part-time activity for each monitor.

How RMS Operates

The scheme built on the experience of researchers from the Kenyan Medical Research Institute (KEMRI)/ Welcome Research Program in Kilifi and the Uganda Virus Research Institute –International AIDS Vaccine Initiative (UVRI-IAVI) who have developed an in-house system for monitoring trials. The scheme is a partnership of 16 research and academic institutions in six African countries (Tanzania, Uganda, Kenya, Sudan, Rwanda and Ethiopia). The partner institutions nominated members to constitute the 25- member RMS who are periodically trained in monitoring workshops or refresher training courses. Experienced monitors are paired with new or less experienced monitors for ‘hands-on’ mentoring in order to increase and sustain capacity (See appendix A). A series of exchange monitoring activities are conducted by the monitors who are paired to conduct trials at institutions where they are not employed.  A number of trials (vaccine trials, drug safety studies, epidemiological studies and longitudinal intervention studies) across Africa have been monitored and those planned to be monitored by the scheme (see appendix B).

In addition, consultative requests for monitoring services from Principal investigators (PI) are conducted at a fee. Activities of the scheme are coordinated by an experienced monitor and researcher, Dr. Annet Nanvubya who is based the EACCR secretariat at the Uganda Virus Research Institute in Entebbe. She liaises between monitors, research institutes and investigators to ensure that monitoring activities are conducted as planned. The RMS coordinator is responsible for developing monitoring tools, providing oversight and logistical support to Monitors.

Impact of Reciprocal Monitoring Scheme

  1. The cross-site collaboration of partner institutions has contributed to the strengthening of internal Quality Management processes which in turn has led to the improvement of the quality of Clinical Trials in Eastern Africa.
  2. The scheme has contributed to the development of practical and cost efficient on-site monitoring among member institutions.
  3. It has also contributed to the accelerated search of new or better drugs, vaccines and interventions to control the most targeted infectious diseases in East Africa such as TB, Malaria and HIV.

 Sustainability plan

The scheme came up with the following sustainability

  1. Sharing of monitoring costs with study sites/Principal Investigators
  2. Conducting consultative services at a fee
  3. Minimize recruitment of fresh monitors  
  4. Maximize the use of skills from 12 experienced Monitors trained by the scheme
  5. Promote in country monitoring to save on travel costs 

 

EACCR2 Partners

 

©Copyright 2009 - 2025, East African Consortium for Clinical Research

  • Links
    • Contact Us
    • Terms & Conditions
    • Accessibility
    • Privacy Policy
The Global Health Network is a World Health Organization collaborating centre for Research Information Sharing, E-learning, and Capacity Development
  • twitter icon
  • facebook icon

EACCR3 is part of the EDCTP2 Programme supported by the European Union under grant agreement CSA2020NoE-3102